Medical News
/ Published on August 17, 2001
Experimento controlado, randomizado y prospectivo
Efecto de la temperatura en náuseas durante la angiografía fluoresceínica
El calentamiento del colorante de fluoresceína no alteraría significativamente la incidencia de náuseas reportadas con FA.
Los pacientes fueron asignados alternativamente a FA empleando colorante a temperatura ambiente (grupo de control) y colorante precalentado a temperatura corporal (grupo de estudio). Todos los pacientes fueron enmascarados a la temperatura del colorante. Después de realizado FA, los pacientes fueron cuestionados en referencia a los efectos adversos que hallan podido experimentar. De esta manera, los investigadores buscaban medir la ausencia o presencia de náuseas asociadas con FA.
Los resultados obtenidos indicaron que reacciones adversas fueron reportadas para 39 de los angiogramas (7.1%), incluyendo 32 procedimientos en los cuales se informaron náuseas (5.9%). Los investigadores no encontraron diferencia significativa en la frecuencia de náuseas entre los dos grupos (P = 0.28). El tamaño de la muestra empleada permitió un 80% de capacidad para detectar una diferencia significativa clínicamente del 4% de los efectos adversos en uno de los grupos y del 10% en el otro, cuando fueron examinados a un nivel de significación del 5%.
Los investigadores del estudio arribaron a la conclusión de que el calentamiento del colorante de fluoresceína no alteró significativamente la incidencia de náusea reportadas con FA.
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