💪 ONCOLOGÍA | ENSAYO CLÍNICO PIONERO
El CHALLENGE Trial (CO21) es el primer ensayo clínico aleatorizado que demuestra el impacto directo del ejercicio en la supervivencia y marcó un hito: 889 pacientes con cáncer de colon de 6 países en un seguimiento de 8 años.
RESULTADOS:
📈 Año 5: 80% libre de enfermedad vs. 74% (grupo control)
📈 Año 8: Supervivencia global 90% vs. 83%
📉 Riesgo de mortalidad 37% MENOR con programa estructurado
📉 Riesgo de recurrencia 28% MENOR
Un incremento de 10 MET-horas/semana se asocia con reducción de 24% en mortalidad por todas las causas. Caminar ~60 min/día la mayoría de días genera ~18 MET-horas semanales.
💡 APLICACIÓN CLÍNICA: No requiere alto nivel de actividad—"algo de ejercicio es mejor que nada". Incluso 10-20 minutos diarios muestran beneficio y es efectivo en todos los grupos etarios.
Fuente: Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
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