Diversos estudios han confirmado la capacidad de interferón alfa para el control ocular en la enfermedad de Behçet. Ahora, un estudio de la Universidad de Aberdeen (Reino Unido) concluye que también puede ser de utilidad en el tratamiento de uveítis severas y refractarias.
En este estudio prospectivo, publicado en “American Journal of Ophthalmology”, 12 pacientes con uveítis que amenazaba la visión fueron tratados diariamente con el fármaco. Durante el seguimiento promedio de 11 meses, se observó una respuesta clínica positiva en el 83% de los pacientes, con una mejora de la agudeza visual media en logMAR 0,54 a 0,2 (p<0,001), mientras que la puntuación de la oftalmoscopia binocular indirecta pasó de 1,0 a 0,5 (p<0,05) al mes de tratamiento.
American Journal of Ophthalmology 2007;144:55-61.e2
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