La vacuna contra el VRS de prefusión alcanza eficacia demostrable para prevenir hospitalizaciones en adultos ≥60 años
El ensayo DAN-RSV proporciona la primera evidencia de efectividad real en población general —no solo en contextos experimentales controlados—.
DATOS CLAVE DEL ENSAYO:
- Población: 131 276 adultos ≥60 años aleatorizados 1:1 a VRSpreF vs sin vacuna
- Período: Temporada de VRS 2024-25
- Eficacia primaria: Hospitalización por enfermedad respiratoria asociada a VRS: 83,3 % (IC 95 %: 42,9-96,9 %)
- Punto secundario: Reducción 15,2 % en hospitalizaciones por enfermedad respiratoria de cualquier causa.
💪Estimaciones proyectadas postulan 416 500 a 655 500 eventos prevenibles por año de hospitalizaciones por VRS en adultos mayores.
📋RSV Prefusion F Vaccine for Prevention of Hospitalization in Older Adults
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