👁️ ¿Semaglutida y riesgo de ceguera? Lo que se sabe (y lo que aún no)
En el debate actual sobre los riesgos oculares de los agonistas de GLP-1, la evidencia con semaglutida es mixta pero alerta a la prudencia.
➡️ Algunos estudios observacionales recientes no hallaron un aumento significativo de retinopatía diabética.
➡️ Pero otras investigaciones —incluyendo un metaanálisis 2025— señalan una posible mayor incidencia de neuropatía óptica isquémica anterior no arterítica (NAION), una causa rara de pérdida visual súbita.
🔎 Conclusión: la semaglutida no está demostrada como causa directa de ceguera, pero en pacientes con diabetes —sobre todo con retinopatía previa o riesgo vascular— se sugiere:
-Hacer fondo de ojo antes de iniciar tratamiento,
-Evitar descensos abruptos de glucemia,
-Mantener un monitoreo oftalmológico cuidadoso.
Fuente: Springer Nature
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