Aparte del gen mutado causante de la fibrosis quística, pequeñas diferencias en otros genes pueden modificar significativamente la gravedad de esta enfermedad, según un gran estudio multicéntrico que publica "The New England Journal of Medicine".
Dirigido por investigadores de la University of North Carolina y la Case Western University, demuestra por primera vez que variantes específicas del gen del factor de crecimiento transformador beta 1 (TGFb1) son responsables en gran medida de la gravedad de la fibrosis quística.
En la investigación participaron unos 1.300 pacientes y, según los autores, tiene importantes implicaciones futuras en el pronóstico y tratamiento de estos enfermos.
Webs Relacionadas
New England Journal of Medicine
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Publicado el 9 de octubre de 2005
Investigación
Variantes genéticas y fibrosis quística
Nuevos aportes al conicimiento de la genética de una grave enfermedad.
Aparte del gen mutado causante de la fibrosis quística, pequeñas diferencias en otros genes pueden modificar significativamente la gravedad de esta enfermedad, según un gran estudio multicéntrico que publica "The New England Journal of Medicine".
Dirigido por investigadores de la University of North Carolina y la Case Western University, demuestra por primera vez que variantes específicas del gen del factor de crecimiento transformador beta 1 (TGFb1) son responsables en gran medida de la gravedad de la fibrosis quística.
En la investigación participaron unos 1.300 pacientes y, según los autores, tiene importantes implicaciones futuras en el pronóstico y tratamiento de estos enfermos.
Webs Relacionadas
New England Journal of Medicine