La idea se basa en proteger los pulmones de la acción de los radicales libres cuando son extraídos del donante. Si el daño producido es extenso, el sistema inmunitario del receptor puede atacar al nuevo órgano, lo cual compromete la vida del paciente.
La nueva técnica consiste en utilizar una sustancia antioxidante una enzima llamada catalasa-, unida a un anticuerpo que actúa sobre el tejido pulmonar. En experimentos con ratas, han comprobado que ello protege los pulmones extraídos frente a la acción de los radicales libres.
En opinión de los investigadores, si el procedimiento ofrece resultados similares en el ser humano, los médicos podrían utilizarlo para incrementar las tasas de éxito del trasplante pulmonar.
Webs Relacionadas
University of Pennsylvania
http://www.upenn.edu/
Nature Biotechnology
http://www.nature.com/nbt/
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