El fármaco actúa bloqueando el factor de crecimiento endotelial vascular, reduciendo así el suministro de sangre al tumor. En el estudio se ha observado que prolonga la supervivencia de los pacientes comparado a placebo.
No obstante, no se ha demostrado que disminuya el tamaño del tumor, tras ensayarlo en un grupo de 116 pacientes con cáncer de riñón extendido a otros órganos.
La estrategia es conocida como antiangiogénesis y hay en ella depositadas grandes esperanzas en el campo de la oncología. Consiste en bloquear la acción de proteínas implicados en la formación de nuevos vasos que nutren los tumores y que son esenciales para su crecimiento. Este nuevo tipo de fármacos podrá utilizarse en combinación con otras terapias para tratar cánceres que no responden a los convencionales.
Webs Relacionadas
Genentech
http://www.genentech.com/
Reunión anual de la ASCO
http://www.asco.org/
American Society of Clinical Oncology (ASCO)
http://www.asco.org/
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