En el "Journal of Clinical Investigation", investigadores de la Universidad de Pennsylvania (Estados Unidos) y del Hadassah Medical Center de Jerusalén (Israel) explican los resultados conseguidos con su técnica, basada en la idea de que una proteína llamada HSP-70 puede limitar la inflamación, la destrucción de las células pulmonares y la acumulación de ciertas proteínas, que caracterizan el citado síndrome, cuya causa se desconoce.
Utilizaron un virus inocuo para liberar el gen de la HSP-70 en los pulmones de las ratas, algunas de las cuales presentaban el síndrome. La terapia tuvo un efecto dramático, señalan los autores, mejorando algunos de los síntomas, como la acumulación de fluidos, y disminuyendo a la mitad la tasa de muerte a las 48 horas.
Aunque es todavía muy pronto para plantearse el inicio de ensayos clínicos con este procedimiento, los investigadores lo consideran muy prometedor para una enfermedad potencialmente fatal y bastante frecuente.
Webs Relacionadas
University of Pennsylvania
http://www.upenn.edu/
Journal of Clinical Investigation
http://www.jci.org/
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