Revisando el estudio del Grupo Sueco de Cáncer de Mama, los autores hallaron que entre las mujeres con cáncer de mama que tomaron tamoxifeno durante dos años, 381 fallecieron más adelante por causas diferentes al cáncer, por sólo 307 de las que se medicaron con dicho fármaco durante cinco años.
En el grupo de dos años, 163 mujeres fallecieron debido a enfermedad cardiovascular; en cambio, en el grupo de cinco años, fallecieron 136. A causa de coronariopatías, fallecieron 78 mujeres, del grupo de dos años, y 54, del grupo de cinco años.
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