Noticias médicas
/ Publicado el 9 de diciembre de 2001
Cancer de pulmon a pequeñas celulas
Irradiación profiláctica craneal en cancer de pulmon a pequeñas celulas.
Esta recomendad la irradiacion profilactica en pacientes con cancer de pulmon a pequeñas celulas que hayan alcanzado respuesta completa
Fuente:
En respuesta a estos interrogantes se realizó un metaanálisis en varios centros canadienses (Lung Cancer Disease Site Group.Ontario)
Se realizó una revisión sistemática de la literatura publicada para obtener una guía práctica basada en la evidencia.
Se concluyó que para pacientes que han alcanzado la respuesta completa después de la terapia de inducción, hay evidencia de un beneficio en la Sv libre de enfermedad y la SV global .No hay suficiente evidencia para hacer una definitiva recomendación respecto de la dosis de RT. Existe alguna evidencia que 30-36 Gy en 2-3 Gy/fracción produce mejores resultados que dosis menores o fraccionamientos menos agresivos.el esquema más utilizado es de 25 Gy en 10 fracciones, en 2 semanas. No hay evidencia en cuanto al timing ideal entre la PCI y la QT .
Como conclusión puede decirse que en pacientes portadores de SCLC que hayan alcanzado la respuesta completa la PCI está recomendada .
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