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La investigación, cuyos resultados han sido publicados en el último número de la revista "Anesthesiology", se realizó en ratas, y ha permitido demostrar que manipulando farmacológicamente los receptores específicos de la serotonina, los resultados analgésicos del paracetamol se potencian.
Al mismo tiempo, los científicos han comprobado que disminuían los efectos adversos que producía al combinarlo con otros compuestos, ya que el paracetamol suele administrarse asociado a la codeína, cafeína o antihistamínicos, pero es la primera vez que se combina con fármacos que actúan sobre los receptores serotoninérgicos.
Según el Dr. Micó, "esta combinación puede ser una nueva estrategia analgésica en el futuro, ya que se pueden crear fármacos completamente nuevos y más baratos". "De hecho, ya existen empresas farmacéuticas interesadas en integrarlo en sus proyectos de I+D", añadió.
Webs Relacionadas
Universidad de Cadiz
http://www.uca.es/
Anesthesiology
http://www.anesthesiology.org/