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Los investigadores utilizaron macacos para estudiar la naturaleza de las respuestas inmunes de los linfocitos T gamma delta, un grupo de células inmunes que se descubrió hace pocos años. Los evaluaron tras haberlos infectado con una bacteria emparentada con el bacilo de la tuberculosis, conocida como BCG, y posteriormente la reinocularon. Entonces se evaluó la respuesta de los linfocitos T, comprobando que a los 4-6 días de la reinoculación había concentraciones elevadas en sangre de linfocitos T gamma delta. Los niveles eran nueva veces más elevados que con la infección primaria.
Webs Relacionadas
Science
http://www.sciencemag.org/
Beth Israel Deaconess Medical Center
http://www.bidmc.harvard.edu/
Noticias médicas
Publicado el 25 de abril de 2002
Tuberculosis
Identificada una respuesta inmunológica a la infección por el bacilo de la tuberculosis
En "Science", un equipo del Beth Israel Deaconess Medical Center (Estados Unidos) ha encontrado que un grupo de glóbulos blancos es capaz de guardar "recuerdo" para lanzar una respuesta inmunológica sostenida contra la bacteria causante de la tuberculosis. El hallazgo puede ser importante para conocer mejor cómo el organismo combate la infección y para desarrollar una vacuna más efectiva contra la enfermedad, dado que la de la existente es cuestionada en adultos.
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