La diabetes que se desarrolla durante el embarazo normalmente desaparece después del parto. No obstante, a menudo se reactiva en mujeres que han padecido diabetes gestacional.
Los investigadores estudiaron a 170 mujeres, con historial de diabetes gestacional, las cuales tenían tolerancia normal a la glucosa o deterioro de esa tolerancia, a partir de seis semanas después del parto.
Tras los cuatro años siguientes, 18 mujeres (10,6%) se convirtieron en diabéticas. De ellas, en el comienzo del estudio, tenían tolerancia normal a la glucosa y las otras nueve, deterioro de esa tolerancia.
Los autores hallaron altos niveles de homocisteína posparto se asociaban con inicio de diabetes, sin que influyese ni la edad, el peso corporal o el historial familiar de diabetes.
Estos resultados indican que una hiperhomocisteinemia en el período inmediato del posparto, en madres que han tenido diabetes gestacional, es una factor de riesgo de desarrollo posterior de diabetes.
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Ajou University School of Medicine
Diabetes Care
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