Analizando los genes que se encuentran activos en las células tumorales, investigadores del Instituto Nacional del Cáncer de Estados Unidos, en colaboración con científicos de Shanghai, han podido predecir qué carcinomas hepatocelulares tienen más probabilidades de extenderse a otras partes del organismo.
Publican sus resultados en "Nature Medicine", donde escriben que la identificación de ese patrón genético único para las metástasis de este tipo de tumor podrá ayudar a los médicos a decidir la mejor estrategia terapéutica para cada paciente.
Además, han logrado identificar un gen específico que es necesario para el desarrollo de metástasis. Se trata del gen de la osteopontina, que puede llegar a ser un marcador diagnóstico de las metástasis, así como una posible diana terapéutica.
Nature Medicine 2003;10.1038/nm843
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National Cancer Institute
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