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Uma nova pesquisa apresentada no Pregnancy Meeting 2026 da Society for Maternal-Fetal Medicine (SMFM) revelou que não há qualquer associação entre a vacinação materna com vacinas de mRNA contra a COVID‑19 durante a gestação e o desenvolvimento de autismo ou outros problemas neurodesenvolvimentais nas crianças.
As vacinas de mRNA contra a COVID‑19, indicadas e consideradas seguras em qualquer fase da gestação, continuam sendo recomendadas para proteger a saúde materna e neonatal.
Pesquisadores da Maternal-Fetal Medicine Units Network acompanharam 434 crianças entre 18 e 30 meses de idade em um estudo prospectivo multicêntrico entre maio de 2024 e março de 2025. Dessas, 217 crianças eram filhas de mães que recebram ao menos uma dose da vacina de mRNA durante a gravidez ou até 30 dias antes da concepção e as outras 217 eram filhas de mães não vacinadas com mRNA nesse período. Os resultados mostraram ausência completa de diferença nos desfechos avaliados entre os dois grupos.
“Os desfechos neurodesenvolvimentais das crianças cujas mães receberam a vacina contra a COVID‑19 durante a gestação ou pouco antes não diferem daqueles observados nas crianças de mães que não receberam o imunizante”, afirmou o pesquisador sênior George R. Saade, MD, professor e diretor de Obstetrícia e Ginecologia da Old Dominion University.
Segundo Brenna L. Hughes, MD, MSc, professora da Duke University:
“O estudo, conduzido com rigor dentro de uma rede de ensaios clínicos do NIH, traz resultados tranquilizadores sobre a saúde a longo prazo das crianças cujas mães receberam a vacina durante a gestação.”
O resumo da pesquisa “Association between SARS-CoV-2 vaccine in pregnancy and child neurodevelopment at 18–30 months” será publicado na edição de fevereiro de 2026 da revista Pregnancy.