Así, los investigadores consideran que la enorme diversidad genética del VIH se debe a la diversidad genética de los HLA, moléculas que varían de persona a persona.
Explican que el VIH es difícil de tratar o prevenir con una vacuna debido a su alta capacidad de mutación. En su estudio pudieron comprobar que 473 pacientes infectados presentaban todos distintas secuencias de ADN del virus.
Además, a su juicio, no se trata de mutaciones al azar, sino cambios de los aminoácidos del virus destinados a impedir que sean reconocidos por HLA particulares presentes en el paciente.
La investigación ayuda a comprender por qué los niveles en sangre de VIH varían de persona a persona.
Webs Relacionadas
Science
http://www.sciencemag.org/
Royal Perth Hospital
http://www.rph.wa.gov.au/
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