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Un equipo de la Universidad de California, en San Diego, ha ensayado este tratamiento en un grupo de 116 pacientes, y observó que la prednisona sí que parece ayudar a los afectados a recuperar audición.
El estudio se diseñó para confirmar si el metotrexato podía mantener la mejoría auditiva que se consigue inicialmente con la prednisona. Se administró este esteroide a altas dosis durante un mes a los pacientes para distribuirlos después en dos grupos, que recibieron metotrexato o placebo, respectivamente. Sin embargo, los resultados indican que el metotrexato no es superior al placebo, y los 67 pacientes que recibieron el fármaco abandonaron el tratamiento al observarse una progresión de su pérdida auditiva.
Webs Relacionadas
University of California, San Diego
http://www.ucsd.edu/
JAMA
http://jama.ama-assn.org/