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Investigadores de la Universidad de Sydney en Australia han encontrado una asociación significativa entre la DMAE tardía y el deterioro cognitivo en personas mayores que parece ser independiente del empeoramiento visual. Esta relación fue más débil, pero aún significativa, tras excluir los ítem visuales del Mini-Mental State Examination (MMSE).
En este estudio, publicado en “Gerontology”, analizaron los datos de las 3.509 personas incluidas en el Blue Mountains Eye Study, de las que el 1,5% (50) y el 8,3% (273) presentaban DMAE tardía y precoz, respectivamente.
Se identificó deterioro cognitivo en el 18% del grupo con DMAE tardía y en el 8,4% con DMAE precoz, frente al 2,6% en las personas sin DMAE. Tras el ajuste multivariante, la DMAE tardía se asoció a una puntuación MMSE inferior a la normal (OR: 2,2) y a deterioro cognitivo (OR: 3,7).
Gerontology 2006;52:353-358