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Investigaciones previas habían indicado que los pacientes con esta enfermedad generan menores cantidades de óxido nítrico producido por la proteína eNOS. Para su experimento, alteraron genéticamente la producción de la proteína en ratones con insuficiencia cardíaca para que fuera entre 10 y 12 veces superior a la normal. En este tratamiento, la supervivencia de los animales aumentó un 43%.
Webs Relacionadas
Proceedings of the National Academy of Sciences
http://www.pnas.org/
Noticias médicas
Publicado el 9 de abril de 2003
Insuficiencia cardíaca
Aumentar los niveles de una proteína mejora la insuficiencia cardíaca
Incrementar los niveles de una proteína llamada sintasa del óxido nítrico endotelial (eNOS), que ayuda a regular los niveles de óxido nítrico en sangre, mejora la insuficiencia cardíaca en ratones, según muestran investigadores de la Louisiana State University en la edición electrónica de "Proceedings of the National Academy of Sciences".