La administración de este fármaco, que es una proteína mutante de IL-4, previno la eosinofilia de las vías aéreas inducida por antígenos, así como la hipersensibilidad de las vías aéreas.
Los autores explican que la IL-4 y la IL-13 desempeñan un papel importante en el asma alérgica y que los agentes que bloquean el complejo de las dos interleuquinas pueden proporcionar beneficios clínicos interesantes.
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Published on June 13, 2001
Hiperreactividad de la vía aérea
Antagonistas del receptor de la IL-4 para el asma alérgica
Un trabajo publicado en el "Journal of Immunology" muestra los positivos resultados obtenidos con un producto experimental que bloquea el receptor de la interleuquina 4 (IL-4) en un modelo de ratón con asma de tipo alérgico.
Fuente: J Immunol 2001 166: 5792-5800
La administración de este fármaco, que es una proteína mutante de IL-4, previno la eosinofilia de las vías aéreas inducida por antígenos, así como la hipersensibilidad de las vías aéreas.
Los autores explican que la IL-4 y la IL-13 desempeñan un papel importante en el asma alérgica y que los agentes que bloquean el complejo de las dos interleuquinas pueden proporcionar beneficios clínicos interesantes.