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Investigadores de la Universidad de Tohoku señalan que algunos fármacos de esta familia, como el captopril o el perindopril, capaces de atravesar la barrera hematoencefálica, parecen frenar la progresión del Alzheimer.
Los autores compararon el estado mental de 162 enfermos de Alzheimer antes y después de ser tratados con inhibidores de la ECA que pueden cruzar la barrera hematoencefálica, con otros de la misma familia que no la atraviesan y con antagonistas del calcio. Al cabo de un año de tratamiento, comprobaron que el deterioro mental era menor en aquellos pacientes que recibieron inhibidores de la ECA que alcanzan el cerebro, en comparación con aquellos enfermos que recibieron otros fármacos.
Webs Relacionadas
Tohoku University
http://www.tohoku.ac.jp/
Neurology
http://www.neurology.org/