1. Watson, N. et al. Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. J. Clin. Sleep Med. 11, 931–952 (2015).
2. Hirshkowitz, M. et al. National Sleep Foundation’s updated sleep duration recommendations: final report. Sleep Heal. 1, 233–243 (2015).
3. Liu, Y. et al. Prevalence of healthy sleep duration among adults — United States, 2014. MMWR Morb. Mortal. Wkly Rep. 65, 137–141 (2016).
4. Grandner, M. A., Patel, N. P., Gehrman, P. R., Perlis, M. L. & Pack, A. I. Problems associated with short sleep: bridging the gap between laboratory and epidemiological studies. Sleep Med. Rev. 14,239–247 (2010).
5. Wheaton, A. G., Jones, S. E., Cooper, A. C. & Croft, J. B. Short sleep duration among middle school and high school students — United States, 2015. MMWR Morb. Mortal. Wkly Rep. 67, 85–90 (2018).
6. Schutte-rodin, S. et al. Clinical guideline for the evaluation and management of chronic insomnia in adults. J. Clin. Sleep Med. 4, 487–504 (2008).
7. Young, T. et al. The occurrence of sleep-disordered breathing among middle-aged adults. N. Engl. J. Med. 328, 1230–1235 (1993).
8. Peppard, P. E. et al. Increased prevalence of sleep-disordered breathing in adults. Am. J. Epidemiol. 177, 1006–1014 (2013).
9. Heinzer, R. et al. Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study. Lancet Respir. Med. 3, 310–318 (2015).
10. Chin, K. et al. Associations between obstructive sleep apnea, metabolic syndrome, and sleep duration, as measured with an actigraph, in an urban male working population in Japan. Sleep 33, 89–95 (2010).
11. Vgontzas, A. N. et al. Insomnia with short sleep duration and mortality: the Penn State cohort. Hypertension 33, 1159–1164 (2010).
12. Vgontzas, A. N., Fernandez-Mendoza, J., Liao, D. & Bixler, E. O. Insomnia with objective short sleep duration: the most biologically severe phenotype of the disorder. Sleep Med. Rev. 17, 241–254 (2013).
13. Ren, R. et al. Objective but not subjective short sleep duration is associated with hypertension in obstructive sleep apnea. Hypertension 72, 610–617 (2018).
14. Priou, P. et al. Cumulative association of obstructive sleep apnea severity and short sleep duration with the risk for hypertension. PLOS ONE 9, 1–12 (2014).
15. Tobaldini, E. et al. Sleep, sleep deprivation, autonomic nervous system and cardiovascular diseases. Neurosci. Biobehav. Rev. 74, 321–329 (2017).
16. Li, X. et al. U-shaped relationships between sleep duration and metabolic syndrome and metabolic syndrome components in males: a prospective cohort study. Sleep Med. 16, 949–954 (2015).
17. Kim, J. Y. et al. A prospective study of total sleep duration and incident metabolic syndrome: the ARIRANG study. Sleep Med. 16, 1511–1515 (2015).
18. Gottlieb, D. J. et al. Association of sleep time with diabetes mellitus and impaired glucose tolerance. Arch. Intern. Med. 165, 863–867 (2005).
19. Wu, Y., Zhai, L. & Zhang, D. Sleep duration and obesity among adults: a meta-analysis of prospective studies. Sleep Med. 15, 1456–1462 (2014).
20. Sabanayagam, C. & Shankar, A. Sleep duration and cardiovascular disease: results from the National Health Interview Survey. Sleep 33, 1037–1042 (2010).
21. Sauvet, F. et al. Effect of acute sleep deprivation on vascular function in healthy subjects. J. Appl. Physiol. 108, 68–75 (2010).
22. Tobaldini, E. et al. One night on-call: sleep deprivation affects cardiac autonomic control and inflammation in physicians. Eur. J. Intern. Med. 24, 664–670 (2013).
23. Zhong, X. et al. Increased sympathetic and decreased parasympathetic cardiovascular modulation in normal humans with acute sleep deprivation. J. Appl. Physiol. 98, 2024–2032 (2005).
24. Dettoni, J. L. et al. Cardiovascular effects of partial sleep deprivation in healthy volunteers. J. Appl. Physiol. 113, 232–236 (2012).
25. Takase, B. et al. Effects of chronic sleep deprivation on autonomic activity by examining heart rate variability, plasma catecholamine, and intracellular magnesium levels. Biomed. Pharmacother. 58, 35–39 (2004).
26. Grimaldi, D., Carter, J. R., Van Cauter, E. & Leproult, R. Adverse impact of sleep restriction and circadian misalignment on autonomic function in healthy young adults. Hypertension 68, 243–250 (2016).
27. Spiegel, K., Leproult, R. & Van Cauter, E. Impact of sleep debt on metabolic and endocrine function. Lancet 354, 1435–1439 (1999).
28. Neufeld, E. V., Carney, J. J., Dolezal, B. A., Boland, D. M. & Cooper, C. B. Exploratory study of heart rate variability and sleep among emergency medical services shift workers. Prehospital Emerg. Care 21, 18–23 (2017).
29. Chung, M. et al. Recovery after three-shift work: relation to sleep-related cardiac neuronal regulation in nurses. Ind. Health 1, 24–30 (2012).
30. Su, T. C. et al. Elevated blood pressure, decreased heart rate variability and incomplete blood pressure recovery after a 12-hour night shift work. J. Occup. Health 50, 380–386 (2008).
31. Yamasaki, F., Schwartz, J. E., Gerber, L. M., Warren, K. & Pickering, T. G. Impact of shift work and race/ ethnicity on the diurnal rhythm of blood pressure and catecholamines. Hypertension 32, 417–423 (1998).
32. Irwin, M. R. Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation. Arch. Intern. Med. 166, 1756 (2006).
33. Irwin, M. R., Witarama, T., Caudill, M., Olmstead, R. & Breen, E. C. Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans. Brain. Behav. Immun. 47, 86–92 (2015).
34. Sauvet, F. et al. Vascular response to 1 week of sleep restriction in healthy subjects. A metabolic response? Int. J. Cardiol. 190, 246–255 (2015).
35. Vgontzas, A. N. et al. Circadian interleukin-6 secretion and quantity and depth of sleep.
J. Clin. Endocrinol. Metab. 84, 2603–2607 (1999).
36. Meier-Ewert, H. K. et al. Effect of sleep loss on C-Reactive protein, an inflammatory marker of cardiovascular risk. J. Am. Coll. Cardiol. 43, 678–683 (2004).
37. van Leeuwen, W. M. A. et al. Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP. PLOS ONE 4, e4589 (2009).
38. Ferrie, J. E. et al. Associations between change in sleep duration and inflammation: findings on C-reactive protein and interleukin 6 in the Whitehall II study. Am. J. Epidemiol. 178, 956–961 (2013).
39. Miller, M. a et al. Gender differences in the cross-sectional relationships between sleep duration and markers of inflammation: Whitehall II study. Sleep 32, 857–864 (2009).
40. Faraut, B., Boudjeltia, K. Z., Vanhamme, L. & Kerkhofs, M. Immune, inflammatory and
cardiovascular consequences of sleep restriction and recovery. Sleep Med. Rev. 16, 137–149 (2012).
41. Boudjeltia, K. et al. Temporal dissociation between myeloperoxidase (MPO)-modified LDL and MPO elevations during chronic sleep restriction and recovery in healthy young men. PLOS ONE 6, e28230 (2011).
42. Weil, B. R. et al. Short sleep duration is associated with enhanced endothelin-1 vasoconstrictor tone. Can. J. Physiol. Pharmacol. 88, 777–781 (2010).
43. Nakazaki, C. et al. Association of insomnia and short sleep duration with atherosclerosis risk in the elderly. Am. J. Hypertens. 25, 1149–1155 (2012).
44. Matthews, K. A., Dahl, R. E., Owens, J. F., Lee, L. & Hall, M. Sleep duration and insulin resistance in healthy black and white adolescents. Sleep 35, 1353–1358 (2012).
45. Rodrigues, De. Bernardi A. M. et al. Association of sleep deprivation with reduction in insulin sensitivity as assessed by the hyperglycemic clamp technique in adolescents. JAMA Pediatr. 170, 487–494 (2016).
46. Reynolds, A. C. et al. Impact of five nights of sleep restriction on glucose metabolism, leptin and testosterone in young adult men. PLOS ONE 7, e41218 (2012).
47. Donga, E. et al. Partial sleep restriction decreases insulin sensitivity in type 1 diabetes. Diabetes Care 33, 1573–1577 (2010).
48. Francesco, T., Peverini, F., De Benedetto, M. & De Nuccio, F. Obstructive sleep apnea syndrome: blood viscosity, blood coagulation abnormalities, and early atherosclerosis. Lung 191, 1–7 (2013).
49. Robinson, G. V., Pepperell, J. C. T., Segal, H. C., Davies, R. J. O. & Stradling, J. R. Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trials. Thorax 59, 777–783 (2004).
50. Kondo, Y. et al. Significant relationship between platelet activation and apnea-hypopnea index in patients with obstructive sleep apnea syndrome. Tokai J. Exp. Clin. Med. 36, 79–83 (2011).
51. Von Känel, R. et al. Association between polysomnographic measures of disrupted sleep and prothrombotic factors. Chest 131, 733–739 (2007).
52. Libby, P. Inflammation and cardiovascular disease mechanisms. Am. J. Clin. Nutr. 83, 456–460 (2006).
53. Visser, M., Bouter, L. M., Mcquillan, G. M., Wener, M. H. & Harris, T. B. Elevated C-reactive protein levels in overweight and obese adults. JAMA 282, 2131–2135 (1999).
54. Danesh, J. et al. Fibrin D-dimer and coronary heart disease prospective study and meta-analysis. Circulation 103, 2323–2327 (2001).
55. Kim, H. C. et al. Multimarker prediction of coronary heart disease risk. J. Am. Coll. Cardiol. 55, 2080–2091 (2010).
56. Münzel, T. et al. Impact of oxidative stress on the heart and vasculature: Part 2 of a 3-Part series. J. Am. Coll. Cardiol. 70, 212–229 (2017).
57. Itani, O., Jike, M., Watanabe, N. & Kaneita, Y. Short sleep duration and health outcomes: a systematic review, meta-analysis, and metaregression. Sleep Med. 32, 246–256 (2017).
58. Chien, K.-L. et al. Habitual sleep duration and insomnia and the risk of cardiovascular events and all-cause death: report from a community-based cohort. Sleep 33, 177–184 (2010).
59. Campanini, M. Z. et al. Agreement between sleep diary and actigraphy in a highly educated Brazilian population. Sleep Med. 35, 27–34 (2017).
60. Lockley, S. W., Skene, D. J. & Arendt, J. Comparison between subjective and actigraphic measurement of sleep and sleep rhythms. J. Sleep Res. 8, 175–183
61. Arora, T., Broglia, E., Pushpakumar, D., Lodhi, T. & Taheri, S. An investigation into the strength of the association and agreement levels between subjective and objective sleep duration in adolescents. PLOS ONE 8, 1–6 (2013).
62. Girschik, J., Fritschi, L., Heyworth, J. & Waters, F. Validation of self-reported sleep against actigraphy. J. Epidemiol. 22, 462–468 (2012).
63. Ross, R. Atherosclerosis — An inflammatory disease. N. Engl. J. Med. 340, 115–126 (1999).
64. Willerson, J. T. Inflammation as a cardiovascular risk factor. Circulation 109, II2–10 (2004).
65. Vgontzas, A. N. et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J. Clin. Endocrinol. Metab. 89, 2119–2126 (2004).
66. Orshal, J. M. & Khalil, R. a. Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R1013–R1023 (2004).
67. Gangwisch, J. E. et al. Short sleep duration as a risk factor for hypertension: analyses of the first National Health and Nutrition Examination survey. Hypertension 47, 833–839 (2006).
68. Cappuccio, F. P. et al. Gender-specific associations of short sleep duration with the Whitehall II study. Hypertension 50, 693–700 (2007).
69. Knutson, K. L. et al. Association between sleep and blood pressure in midlife. Arch. Intern. Med. 169, 1055 (2009).
70. Ridker, P. M. C-reactive protein and the prediction of cardiovascular events among those at intermediate risk moving an inflammatory hypothesis toward consensus. J. Am. Coll. Cardiol. 49, 2129–2138 (2007).
71. Albert, C. M., Ma, J., Rifai, N., Stampfer, M. J. & Ridker, P. M. Prospective study of C-reactive protein, homocysteine, and plasma lipid levels as predictors of sudden cardiac death. Circulation 105, 2595–2599 (2002).
72. Danesh, J. et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N. Engl. J. Med. 350, 1387–1397 (2004).
73. Calvin, A. D. et al. Experimental sleep restriction causes endothelial dysfunction in healthy humans. J. Am. Heart Assoc. 3, 1–7 (2014).
74. Pongratz, G. & Straub, R. H. The sympathetic nervous response in inflammation. Arthritis Res. Ther. 16, 1–12 (2014).
75. Podrez, E. A., Schmitt, D., Hoff, H. F. & Hazen, S. L. Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J. Clin. Invest. 103, 1547–1560 (1999).
76. van Leeuwen, W. M. A. et al. Prolonged sleep restriction affects glucose metabolism in healthy young men. Int. J. Endocrinol. 2010, 108641 (2010).
77. Paneni, F., Diaz Cañestro, C., Libby, P., Lüscher, T. F. & Camici, G. G. The aging cardiovascular system: understanding it at the cellular and clinical levels. J. Am. Coll. Cardiol. 69, 1952–1967 (2017).
78. Miller, M. A., Kandala, N., Kumari, M., Marmot, M. G. & Cappuccio, F. P. Clinical and population studies relationships between sleep duration and von Willebrand factor, factor vii, and fibrinogen Whitehall II study. Arter. Thromb. Vasc. Biol. 30, 2032–2039 (2010).
79. Tosur, Z. et al. The association between sleep characteristics and prothrombotic markers in a population based sample: Chicago area sleep study Sleep Med. 15, 973–978 (2014).
80. Chouchou, F. et al. Sympathetic overactivity due to sleep fragmentation is associated with elevated diurnal systolic blood pressure in healthy elderly subjects: the PROOF-SYNAPSE study. Eur. Heart J. 34, 2122–2131 (2013).
81. Muenter, N. K. et al. Effect of sleep restriction on orthostatic cardiovascular control in humans. J. Appl. Physiol. 88, 966–972 (2000).
82. Sforza, E. et al. Heart rate activation during spontaneous arousals from sleep: effect of sleep deprivation. Clin. Neurophysiol. 115, 2442–2451 (2004).
83. Malliani, A. & Montano, N. Emerging excitatory role of cardiovascular sympathetic afferents in pathophysiological conditions. Hypertension 39, 63–68 (2002).
84. Shen, M. J. & Zipes, D. P. Role of the autonomic nervous system in modulating cardiac arrhythmias. Circ. Res. 114, 1004–1021 (2014).
85. Agarwal, S. K. et al. Cardiac autonomic dysfunction and incidence of atrial fibrillation in a large population-based cohort. J. Am. Coll. Cardiol. 69, 291–299 (2017).
86. Meredith, I. T., Broughton, A., Jennings, G. L. & Esler, M. D. Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias. N. Engl. J. Med. 325, 618–624 (1991).
87. Mancia, G. & Grassi, G. The autonomic nervous system and hypertension. Circ. Res. 114, 1804–1814 (2014).
88. Airaksinen, K. E., Ikaheimo, M. J., Linnaluoto, M. K., Niemela, M. & Takkunen, J. T. Impaired vagal heart rate control in coronary artery disease. Heart 58, 592–597 (1987).
89. Kochiadakis, G. E. et al. Autonomic nervous system activity before and during episodes of myocardial ischemia in patients with stable coronary artery disease during daily life. Pacing Clin. Electrophysiol. 23, 2030–2039 (2000).
90. Huikuri, H. V. et al. Heart rate variability and progression of coronary atherosclerosis.
Arter. Thromb. Vasc. Biol. 19, 1979–1985 (1999).
91. van Bilsen, M. et al. The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology. Eur. J. Hear. Fail. 19,
92. Floras, J. S. & Ponikowski, P. The sympathetic/ parasympathetic imbalance in heart failure with reduced ejection fraction. Eur. Heart J. 36, 1974–1982 (2015).
93. Wang, Y. et al. Chronic sleep fragmentation promotes obesity in young adult mice. Obesity 22, 758–762 (2014).
94. Tracey, K. J. The inflammatory reflex. Nature 420, 853–859 (2002).
95. Itani, O., Kaneita, Y., Murata, A., Yokoyama, E. & Ohida, T. Association of onset of obesity with sleep duration and shift work among Japanese adults. Sleep Med. 12, 341–345 (2011).
96. Cassidy, S., Chau, J. Y., Catt, M., Bauman, A. & Trenell, M. I. Cross-sectional study of diet, physical activity, television viewing and sleep duration in 233 110 adults from the UK Biobank; the behavioural phenotype of cardiovascular disease and type 2
diabetes. BMJ Open 6, e010038 (2016).
97. Venancio, D. P. & Suchecki, D. Prolonged REM sleep restriction induces metabolic syndrome-related changes: mediation by pro-inflammatory cytokines. Brain Behav. Immun. 47, 109–117 (2015).
98. Moraes, D. A., Venancio, D. P. & Suchecki, D. Sleep deprivation alters energy homeostasis through non-compensatory alterations in hypothalamic insulin receptors in Wistar rats. Horm. Behav. 66, 705–712 (2014).
99. Zhan, S. et al. Decrease in circulating fatty acids is associated with islet dysfunction in chronically sleep-restricted rats. Int. J. Mol. Sci. 17, 2102 (2016).
100. Jha, P. K., Foppen, E., Kalsbeek, A. & Challet, E. Sleep restriction acutely impairs glucose tolerance in rats. Physiol. Rep. 4, e12839 (2016).
101. Spiegel, K., Tasali, E., Penev, P. & Van Cauter, E. Brief communication: Sleep curtailment in healthyyoung men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann. Intern. Med. 141, 846–850
102. Broussard, J. L. et al. Insulin access to skeletal muscle is impaired during the early stages of diet-induced obesity. Obesity 24, 1922–1928 (2016).
103. Chapman, C. D. et al. Acute sleep deprivation increases food purchasing in men. Obesity 21, E555–E560 (2013).
104. St-Onge, M.-P., O’Keeffe, M., Roberts, A. L., RoyChoudhury, A. & Laferrere, B. Short sleep duration, glucose dysregulation and hormonal regulation of appetite in men and women. Sleep 35, 1503–1510 (2012).
105. Markwald, R. R. et al. Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc. Natl Acad. Sci. USA 110, 5695–5700 (2013).
106. de Oliveira, E. M. et al. Serum amyloid A production is triggered by sleep deprivation in mice and humans: is that the link between sleep loss and associated comorbidities? Nutrients 9, E311 (2017).
107. DePorter, D. P., Coborn, J. E. & Teske, J. A. Partial sleep deprivation reduces the efficacy of orexin-A to stimulate physical activity and energy expenditure.
Obesity 25, 1716–1722 (2017).
108. Parrish, J. B. & Teske, J. A. Acute partial sleep deprivation due to environmental noise increases weight gain by reducing energy expenditure in rodents. Obesity 25, 141–146 (2017).
109. de Oliveira, E. M. et al. Late effects of sleep restriction: potentiating weight gain and insulin resistance arising from a high-fat diet in mice. Obesity 23, 391–398 (2015).
110. Zhang, S. X. L. et al. Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice. Int. J. Obes. 38, 619–624 (2014).
111. Weyer, C. et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J. Clin. Endocrinol. Metab. 86,
112. Yamauchi, T. et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7, 941–946 (2001).
113. Simpson, N. S., Banks, S., Arroyo, S. & Dinges, D. F. Effects of sleep restriction on adiponectin levels in healthy men and women. Physiol. Rep. 101, 693–698 (2010).
114. Nilsson, P. M., Rööst, M., Engström, G., Hedblad, B. & Berglund, G. Incidence of diabetes in middle-aged men is related to sleep disturbances. Diabetes Care 27, 2464–2469 (2004).
115. Tasali, E., Leproult, R., Ehrmann, D. A. & Van Cauter, E. Slow-wave sleep and the risk of type 2 diabetes in humans. Proc. Natl Acad. Sci. USA 105, 1044–1049 (2008).
116. Benedict, C., Barclay, J. L., Ott, V., Oster, H. & Hallschmid, M. Acute sleep deprivation delays the glucagon-like peptide 1 peak response to breakfast in healthy men. Nutr. Diabetes 3, e78 (2013).
117. Aho, V. et al. Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses. Sci. Rep. 6, 24828 (2016).
118. O’Keeffe, M., Roberts, A. L., Kelleman, M. RoyChoudhury, A. & St-Onge, M.-P. No effects of short-term sleep restriction, in a controlled feeding setting, on lipid profiles in normal weight adults. J. Sleep Res. 22 (2013).
119. Skuladottir, G. V., Nilsson, E. K., Mwinyi, J. & Schioth, H. B. One-night sleep deprivation induces changes in the DNA methylation and serum activity indices of stearoyl-CoA desaturase in young healthy men. Lipids Health Dis. 15, 137 (2016).
120. Broussard, J. L. et al. Sleep restriction increases free fatty acids in healthy men. Diabetologia 58, 791–798 (2015).
121. Riggs, D. W., Yeager, R. A. & Bhatnagar, A. An omics approach for assessing the environmental risk of cardiovascular disease. Circ. Res. 122, 1259–1275 (2018).
122. Cappuccio, F. P., Cooper, D., D.’Elia, L., Strazzullo, P. & Miller, M. A. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur. Heart J. 32, 1484–1492 (2011).
123. Ikehara, S. et al. Association of sleep duration with mortality from cardiovascular disease and other causes for Japanese men and women: the JACC study. Sleep 32, 295–301 (2009).
124. Pepin, J. L. et al. Hypertension and sleep: overview of a tight relationship. Sleep Med. Rev. 18, 509–519 (2014).
125. Gottlieb, D. J. et al. Association of usual sleep duration with hypertension: the Sleep Heart Health Study. Sleep 29, 1009–1014 (2006).
126. Guo, X. et al. Epidemiological evidence for the link between sleep duration and high blood pressure: a systematic review and meta-analysis. Sleep Med. 14, 324–332 (2013).
127. Wang, Q., Xi, B., Liu, M., Zhang, Y. & Fu, M. Short sleep duration is associated with hypertension risk among adults: a systematic review and meta-analysis. Hypertens. Res. 35, 1012–1018 (2012).
128. Wang, Y. et al. Relationship between duration of sleep and hypertension in adults: a meta-analysis. J. Clin. Sleep Med. 11, 1047–1056 (2015).
129. Meng, L., Zheng, Y. & Hui, R. The relationship of sleep duration and insomnia to risk of hypertension incidence: a meta-analysis of prospective cohort studies. Hypertens. Res. 36, 985–995 (2013).
130. Wu, X. et al. Association of self-reported sleep duration and hypertension: results of a Chinese prospective cohort study. Clin. Exp. Hypertens. 38, 514–519 (2016).
131. Kim, J. & Jo, I. Age-dependent association between sleep duration and hypertension in the adult Korean population. Am. J. Hypertens. 23, 1286–1291 (2010).
132. Fang, J. et al. Association of sleep duration and hypertension among US adults varies by age and sex. Am. J. Hypertens. 25, 335–341 (2012).
133. Stranges, S. et al. A population-based study of reduced sleep duration and hypertension: the strongest association may be in premenopausal women. J. Hypertens. 28, 896–902 (2010).
134. Javaheri, S., Storfer-Isser, A., Rosen, C. L. & Redline, S. Sleep quality and elevated
blood pressure in adolescents. Circulation 118, 1034–1040 (2008).
135. Ramos, A. R. et al. Sleep patterns and hypertension using actigraphy in the Hispanic Community Health Study/Study of Latinos. Chest 153, 87–93 (2018).
136. Haack, M. et al. Increasing sleep duration to lower beat-to-beat blood pressure — a pilot study. J. Sleep Res. 22, 295–304 (2013).
137. Acar, G. et al. Acute sleep deprivation in healthy adults is associated with a reduction in left atrial early diastolic strain rate. Sleep Breath. 17, 975–983 (2013).
138. Cakici, M. et al. Negative effects of acute sleep deprivation on left ventricular functions and cardiac repolarization in healthy young adults. Pacing Clin. Electrophysiol. 38, 713–722 (2015).
139. Ozer, O. et al. Acute sleep deprivation is associated with increased QT dispersion in healthy young adults. Pacing Clin. Electrophysiol. 31, 979–984 (2008).
140. Miner, S. E. S. et al. Sleep disruption is associated with increased ventricular ectopy and cardiac arrest in hospitalized adults. Sleep 39, 927–935 (2016).
141. Ayas, N. T. et al. A prospective study of sleep duration and coronary heart disease in women. Arch. Intern. Med. 163, 205–209 (2003).
142. Chandola, T., Ferrie, J. E., Perski, A., Akbaraly, T. & Marmot, M. G. The effect of short sleep duration on coronary heart disease risk is greatest among those with sleep disturbance: a prospective study from the Whitehall II cohort. Sleep 33, 739–744 (2010).
143. Liu, Y., Wheaton, A. G., Chapman, D. P. & Croft, J. B. Sleep duration and chronic diseases among US adults age 45 years and older: evidence from the 2010 Behavioral Risk Factor Surveillance System. Sleep 36, 1421–1427 (2013).
144. King, C. R. et al. Short sleep duration and incident coronary artery calcification. JAMA 300, 2859–2866 (2008).
145. Barger, L. K. et al. Short sleep duration, obstructive sleep apnea, shiftwork, and the risk of adverse cardiovascular events in patients after an acute coronary syndrome. J. Am. Heart Assoc. 6, e006959 (2017).
146. McHill, A. W. & Wright, K. P. J. Role of sleep and circadian disruption on energy expenditure and in metabolic predisposition to human obesity and metabolic disease. Obes. Rev. 18 (Suppl. 1), 15–24 (2017).
147. Rafalson, L., Donahue, R. P. & Trevisan, M. Short sleep duration is associated with the development of impaired fasting glucose: the Western New York Health study. Ann. Epidemiol. 20, 883–889 (2010).
148. Spiegel, K., Tasali, E., Leproult, R. & Van Cauter, E. Effects of poor and short sleep on glucose metabolism and obesity risk. Nat. Rev. Endocrinol. 5, 253–261 (2009).
149. Cohen, D. A. et al. Uncovering residual effects of chronic sleep loss on human performance. Sci. Transl. Med. 2, 14ra3 (2010).
150. Buxton, O. M. et al. Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption. Sci. Transl. Med. 4, 129ra43 (2012).
151. Broussard, J. L., Ehrmann, D. A., Van Cauter, E., Tasali, E. & Brady, M. J. Impaired insulin signaling in human adipocytes after experimental sleep restriction: a randomized, crossover study. Ann. Intern. Med. 157, 549–557 (2012).
152. Cappuccio, F. P. & Miller, M. A. Sleep and cardiometabolic disease. Curr. Cardiol. Rep. 19, 110 (2017).
153. Al Khatib, H. K., Harding, S. V., Darzi, J. & Pot, G. K. The effects of partial sleep deprivation on energy balance: a systematic review and meta-analysis. Eur. J. Clin. Nutr. 71, 614–624 (2017).
154. Nuyujukian, D. S. et al. Sleep duration and diabetes risk in American Indian and Alaska Native participants of a lifestyle intervention project. Sleep 39, 1919–1926 (2016).
155. Heianza, Y. et al. Role of sleep duration as a risk factor for Type 2 diabetes among adults of different ages in Japan: the Niigata Wellness study. Diabet. Med. 31, 1363–1367 (2014).
156. Beihl, D. A., Liese, A. D. & Haffner, S. M. Sleep duration as a risk factor for incident type 2 diabetes in a multiethnic cohort. Ann. Epidemiol. 19, 351–357 (2009).
157. Bromley, L. E., Booth, J. N. 3rd, Kilkus, J. M. Imperial, J. G. & Penev, P. D. Sleep restriction decreases the physical activity of adults at risk for type 2 diabetes. Sleep 35, 977–984 (2012).
158. Booth, J. N. et al. Reduced physical activity in adults at risk for type 2 diabetes who curtail their sleep. Obesity 20, 278–284 (2012).
159. Leproult, R., Deliens, G., Gilson, M. & Peigneux, P. Beneficial impact of sleep extension on fasting insulin sensitivity in adults with habitual sleep restriction. Sleep 38, 707–715 (2015).
160. Krueger, P. M., Reither, E. N., Peppard, P. E., Burger, A. E. & Hale, L. Cumulative exposure to short sleep and body mass outcomes: a prospective study. J. Sleep Res. 24, 629–638 (2015).
161. Li, L., Zhang, S., Huang, Y. & Chen, K. Sleep duration and obesity in children: a systematic review and meta-analysis of prospective cohort studies. J. Paediatr. Child Health 53, 378–385 (2017).
162. Morrissey, B. et al. Sleep duration and risk of obesity among a sample of Victorian school children. BMC Publ. Health 16, 245 (2016).
163. Halal, C. S. E. et al. Short sleep duration in the first years of life and obesity/overweight at age 4 years: a birth cohort study. J. Pediatr. 168, 99–103.e3
164. Martinez, S. M. et al. Is it time for bed? Short sleep duration increases risk of obesity in Mexican American children. Sleep Med. 15, 1484–1489 (2014).
165. Taveras, E. M., Gillman, M. W., Pena, M.-M., Redline, S. & Rifas-Shiman, S. L. Chronic sleep curtailment and adiposity. Pediatrics 133, 1013–1022 (2014).
166. Martinez, S. M. et al. Short sleep duration is associated with eating more carbohydrates and less dietary fat in Mexican American children. Sleep 40,
167. Beebe, D. W. et al. Dietary intake following experimentally restricted sleep in adolescents. Sleep 36, 827–834 (2013).
168. Mullins, E. N. et al. Acute sleep restriction increases dietary intake in preschool-age children. J. Sleep Res. 26, 48–54 (2017).
169. Garaulet, M. et al. Short sleep duration is associated with increased obesity markers in European adolescents: effect of physical activity and dietary habits. The HELENA study. Int. J. Obes. 35, 1308–1317 (2011).
170. Wang, F. et al. Sleep duration and overweight/obesity in preschool-aged children: a prospective study of up to 48,922 children of the Jiaxing birth cohort. Sleep 39, 2013–2019 (2016).
171. Cespedes, E. M. et al. Chronic insufficient sleep and diet quality: contributors to childhood obesity. Obesity 24, 184–190 (2016).
172. Kobayashi, D., Takahashi, O., Deshpande, G. A., Shimbo, T. & Fukui, T. Association between weight gain, obesity, and sleep duration: a large-scale 3-year cohort study. Sleep Breath. 16, 829–833 (2012).
173. Haghighatdoost, F., Karimi, G., Esmaillzadeh, A. & Azadbakht, L. Sleep deprivation is associated with lower diet quality indices and higher rate of general and central obesity among young female students in Iran. Nutrition 28, 1146–1150 (2012).
174. Sun, W. et al. Sleep duration associated with body mass index among Chinese adults. Sleep Med. 16, 612–616 (2015).
175. Kim, K., Shin, D., Jung, G.-U., Lee, D. & Park, S. M. Association between sleep duration, fat mass, lean mass and obesity in Korean adults: the fourth and fifth Korea National Health and Nutrition Examination surveys. J. Sleep Res. 26, 453–460 (2017).
176. Theorell-Haglow, J., Berglund, L., Berne, C. & Lindberg, E. Both habitual short sleepers and long sleepers are at greater risk of obesity: a population-based 10-year follow-up in women. Sleep Med. 15, 1204–1211 (2014).
177. Sperry, S. D., Scully, I. D., Gramzow, R. H.
& Jorgensen, R. S. Sleep Duration and waist circumference in adults: a meta-analysis. Sleep 38, 1269–1276 (2015).
178. Chaput, J.-P., McNeil, J., Despres, J.-P., Bouchard, C. & Tremblay, A. Short sleep
duration as a risk factor for the development of the metabolic syndrome in adults. Prev. Med. 57, 872–877 (2013).
179. Thomson, C. A. et al. Relationship between sleep quality and quantity and weight loss in women participating in a weight-loss intervention trial. Obesity 20, 1419–1425 (2012).
180. Chaput, J.-P. & Dutil, C. Lack of sleep as a contributor to obesity in adolescents: impacts on eating and activity behaviors. Int. J. Behav. Nutr. Phys. Act. 13, 103 (2016).
181. Tasali, E., Chapotot, F., Wroblewski, K. & Schoeller, D. The effects of extended bedtimes on sleep duration and food desire in overweight young adults: a home-based intervention. Appetite 80, 220–224 (2014).
182. Lucassen, E. A. et al. Sleep extension improves neurocognitive functions in chronically sleep deprived obese individuals. PLOS ONE 9, e84832 (2014).
183. Scheer, F. A. J. L., Van Montfrans, G. A., Van Someren, E. J. W., Mairuhu, G. & Buijs, R. M. Daily nighttime melatonin reduces blood pressure in male patients with essential hypertension. Hypertension 43, 192–197 (2004).
184. Grossman, E. et al. Melatonin reduces night blood pressure in patients with nocturnal hypertension. Am. J. Med. 119, 898–902 (2006).
185. Sateia, M. J. International classification of sleep disorders - third edition. Chest 146, 1387–1394 (2014).
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