Pacientes con protocolo para la sedación | 05 NOV 12

Interrupción diaria de la sedación en pacientes graves con ARM

El objetivo de este estudio aleatorizado, controlado, multicéntrico, con 430 pacientes graves, fue comparar la estrategia de sedación según protocolo con la de sedación según protocolo más la interrupción diaria de ésta.
Autor/a: Dres. Mehta S, Burry L, Cook D JAMA. 2012;308(19):doi:10.1001/jama.2012.13872
INDICE:  1. Artículo | 2. Referencias

1. Arroliga AC, Thompson BT, Ancukiewicz M, et al; Acute Respiratory Distress Syndrome Network. Use of sedatives, opioids, and neuromuscular blocking agents in patients with acute lung injury and acute respiratory distress syndrome. Crit Care Med. 2008;36 (4):1083-1088.
2. Kollef MH, Levy NT, Ahrens TS, Schaiff R, Prentice D, Sherman G. The use of continuous iv sedation is associated with prolongation of mechanical ventilation. Chest. 1998;114(2):541-548.
3. Ouimet S, Kavanagh BP, Gottfried SB, Skrobik Y.Incidence, risk factors and consequences of ICU delirium. Intensive Care Med. 2007;33(1): 66-73.
4. Brook AD, Ahrens TS, Schaiff R, et al. Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation. Crit Care Med. 1999; 27(12):2609-2615.
5. Kress JP, Pohlman AS, O’Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med. 2000;342(20):1471-1477.
6. Jacobi J, Fraser GL, Coursin DB, et al; Task Force of the American College of Critical Care Medicine (ACCM) of the Society of Critical Care Medicine (SCCM), American Society of Health-System Pharmacists (ASHP), American College of Chest Physicians. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med. 2002;30(1):119-141.
7. Bucknall TK, Manias E, Presneill JJ. A randomized trial of protocol-directed sedation management for mechanical ventilation in an Australian intensive care unit. Crit Care Med. 2008;36(5):1444-1450.
8. de Wit M, Gennings C, Jenvey WI, Epstein SK. Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients. Crit Care. 2008; 12(3):R70.
9. Anifantaki S, Prinianakis G, Vitsaksaki E, et al. Daily interruption of sedative infusions in an adult medical-surgical intensive care unit: randomized controlled trial. J Adv Nurs. 2009; 65(5):1054-1060.
10. Yiliaz C, Kelebek Girgin N, Ozdemir N, Kutlay O. The effect of nursing-implemented sedation on the duration of mechanical ventilation in the ICU. Ulus Travma Acil Cerrahi Derg. 2010; 16(6):521-526.
11. Mehta S, Burry L, Fischer S, et al; Canadian Critical Care Trials Group. Canadian survey of the use of sedatives, analgesics, and neuromuscular blocking agents in critically ill patients. Crit Care Med. 2006; 34(2):374-380.
12. Patel RP, Gambrell M, Speroff T, et al. Delirium and sedation in the intensive care unit: survey of behaviors and attitudes of 1384 healthcare professionals. Crit Care Med. 2009; 37(3):825-832.
13. Tanios MA, de Wit M, Epstein SK, Devlin JW. Perceived barriers to the use of sedation protocols and daily sedation interruption: a multidisciplinary survey. J Crit Care. 2009; 24(1):66-73.
14. Roberts RJ, de Wit M, Epstein SK, Didomenico D, Devlin JW. Predictors for daily interruption of sedation therapy by nurses: a prospective, multicenter study. J Crit Care 2010; 25(4):660.e1-7.
15. Augustes R, Ho KM. Metaanalysis of randomised controlled trials on daily sedation interruption for critically ill adult patients. Anaesth Intensive Care. 2011; 39(3):401-409.
16. Mehta S, Burry L, Martinez-Motta JC, et al; Canadian Critical Care Trials Group. A randomized trial of daily awakening in critically ill patients managed with a sedation protocol: a pilot trial. Crit Care Med . 2008; 36(7):2092-2099.
17. Riker RR, Picard JT, Fraser GL. Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients. Crit Care Med. 1999; 27(7):1325-1329.
18. Sessler CN, Gosnell MS, Grap MJ, et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002; 166(10):1338-1344.
19. Bergeron N, Dubois M-J, Dumont M, Dial S, Skrobik Y. Intensive Care Delirium Screening Check-list: evaluation of a new screening tool. Intensive Care Med. 2001; 27(5):859-864.
20. Patanwala AE, Duby J, Waters D, Erstad BL. Opioid conversions in acute care. Ann Pharmacother. 2007; 41(2):255-266.
21. Girard TD, Kress JP, Fuchs BD, et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet . 2008; 371(9607): 126-134.
22. Weisbrodt L, McKinley S, Marshall AP, Cole L, Seppelt IM, Delaney A. Daily interruption of sedation in patients receiving mechanical ventilation. Am J Crit Care. 2011; 20(4):e90-e98.
23. Ruokonen E, Parviainen I, Jakob SM, et al; Dexmedetomidine for Continuous Sedation Investigators. Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive Care Med . 2009; 35(2):282-290.
24. Burry L, Perreault M, Williamson D, et al. A prospective evaluation of sedative, analgesic, anti-psychotic and paralytic practices in Canadian mechanically ventilated adults [abstract]. Proc Am Thorac Soc. 2009; 179:A5492.
25. O’Connor M, Bucknall T, Manias E. Sedation management in Australian and New Zealand intensive care units: doctors’ and nurses’ practices and opinions. Am J Crit Care . 2010;19(3):285-295.
26. Burry L, Steinberg M, Kim S, et al; SLEAP Investigators and Canadian Critical Care Trials Group. Clinicians’ perspectives on the use of a sedation protocol or daily sedative interruption in mechanically ventilated patients enrolled in a multicenter sedation trial [abstract]. Intensive Care Med. 2011; 37:S83.



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