✅ ESTUDIO DIG-RHD
La trayectoria de la digoxina sugiere que su utilidad clínica no es inherente al fármaco en sí, sino al contexto fisiopatológico en el que se aplica. Su desplazamiento en la insuficiencia cardíaca moderna no implica una pérdida absoluta de valor, sino una discordancia entre su mecanismo de acción y el modelo predominante de la enfermedad.
La cardiopatía reumática, al reintroducir un escenario donde la hemodinamia diastólica y la frecuencia cardíaca son determinantes, representa un nicho donde la digoxina puede recuperar relevancia.
Este enfoque refuerza la necesidad de abandonar visiones universales y adoptar una medicina basada en fenotipos.
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