La investigación se llevó a cabo con un virus que infecta al ganado vacuno, pero los autores creen que los resultados son aplicables al virus del papiloma humano (VPH), causa de cáncer de cuello uterino.
Explican que una proteína del virus llamada E5 bloquea el transporte de la molécula MHC de clase 1, que normalmente actúa como señal de alarma para el sistema inmunitario. Se sabe que la proteína E5 está presente en tipos de VPH asociados a un alto riesgo de cáncer.
Webs Relacionadas
Oncogene
http://www.nature.com/onc/
University of Glasgow
http://www.gla.ac.uk/
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Publicado el 14 de noviembre de 2002
Sistema inmunitario
Virus del papiloma humano y sistema inmunitario
En "Oncogene" investigadores de la Universidad de Glasgow (Reino Unido) publican haber descubierto cómo los virus del papiloma, escapa a la acción del sistema inmunitario.
Fuente:
La investigación se llevó a cabo con un virus que infecta al ganado vacuno, pero los autores creen que los resultados son aplicables al virus del papiloma humano (VPH), causa de cáncer de cuello uterino.
Explican que una proteína del virus llamada E5 bloquea el transporte de la molécula MHC de clase 1, que normalmente actúa como señal de alarma para el sistema inmunitario. Se sabe que la proteína E5 está presente en tipos de VPH asociados a un alto riesgo de cáncer.
Webs Relacionadas
Oncogene
http://www.nature.com/onc/
University of Glasgow
http://www.gla.ac.uk/