Explican que todas las personas somos portadoras de dicho gen, pero esta mutación en particular la tiene sólo una minoría. El hallazgo ayuda a explicar por qué algunas personas que reciben terapia hormonal pueden presentar un mayor riesgo cardíaco.
Realizaron pruebas genéticas a 1.739 personas que fueron seguidas entre 1971 y 1998. El 20% de estos individuos era portador de dos copias de la variante genética. Estos sujetos tienen un riesgo duplicado respecto al resto de desarrollar cardiopatía grave, sobre todo un riesgo incrementado de infarto de miocardio, que fue la única variable asociada de forma significativa a la variante genética.
Webs Relacionadas
Massachusetts Institute of Technology
http://www.mit.edu
JAMA
http://jama.ama-assn.org/
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