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El calpain-10 produce una enzima involucrada en el procesamiento de la glucosa en las células del músculo esquelético. Una particular forma de este gen, designada como haplotipo 112/121, ya ha sido asociada a una mala tolerancia de la glucosas y a la diabetes tipo 2.
Según informa "Obstetrics and Gynecology", el equipo austríaco analizó las 10 variantes más comunes de calpain-10, en 80 mujeres embarazadas que presentaban diabetes gestacional, y en otras 40 gestantes que no tenían diabetes.
La diabetes gestacional se presentó en todas las mujeres que tenían la forma del haplotipo 121/221.
Estos resultados parecen indicar que el haplotipo 121/221 del gen calpain-10 puede estar asociado con trastornos del metabolismo de la glucosa, durante el embarazo.
Webs Relacionadas
University of Vienna
http://www.univie.ac.at/
Obstetrics and Gynecology
http://www.greenjournal.org/