Investigadores de la University of Texas Medical Branch (Estados Unidos) han ensayado una vacuna que protege aproximadamente al 75% de las mujeres libres de infección por el virus del herpes simple 2 (VHS-2), causante del herpes genital.
No obstante, la efectividad es menor en personas que han estado infectadas por el virus del herpes simple 1 (VHS-1). Pese a ello, los autores consideran que la vacuna puede tener un importante impacto en una gran proporción de la población sexualmente activa, teniendo en cuenta que cuanto menor sea el porcentaje de personas infectadas menos probabilidades hay de propagar el virus.
Se evaluó la vacuna, desarrollada por GlaxoSmithKline, en un grupo de 847 personas libres tanto del VHS-1 como del VHS-2 y en otro de 1.867 sólo libres del VHS-2. Todos los participantes mantenían relaciones sexuales regulares con parejas que habían tenido herpes genital. Los participantes fueron seguidos durante 19 meses.
Entre las personas libres de ambos tipos de virus, la vacuna protegió de la infección al 38% de los participantes, aunque en el caso de las mujeres la proporción se eleva al 73%.
Entre las mujeres que habían estado infectadas por el VHS-1, previno la infección en el 42%.
Webs Relacionadas
University of Texas Medical Branch
http://www.utmb.edu/
New England Journal of Medicine
http://content.nejm.org/
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