En "Cancer Cell" publican su hallazgo, centrado en el oncogén conocido como c-maf, así como en la interacción entre las células del mieloma y otras células de la médula ósea. Utilizando sofisticada tecnología de cribado genético comprobaron que el c-maf estaba presente y se sobreexpresaba en aproximadamente la mitad de todos los casos de mieloma múltiple estudiados, pero no se encontraba en las células plasmáticas normales. Comprobaron posteriormente que el citado oncogén promueve el crecimiento tumoral y, también, que inhibir la función del c-maf en las células del mieloma bloquea la formación del tumor en ratones.
Webs Relacionadas
National Cancer Institute
http://www.cancer.gov/
Cancer Cell
http://www.cancercell.org/
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