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Creen que variaciones similares en el gen humano podrían contribuir a enfermedades caracterizadas por elevados niveles de colesterol, entre ellas la cardiopatía isquémica y la diabetes.
La proteína en cuestión parece regular el metabolismo lipídico en el torrente sanguíneo. Los investigadores encontraron que muestras de tejidos de ratones con baja actividad de la Angpl3 presentan mayores niveles de colesterol total y triglicéridos.
Webs Relacionadas
Nature Genetics
http://www.nature.com/ng/