Los resultados sugieren que el receptor FXR puede ser una diana terapéutica para prevenir o tratar la enfermedad. Los autores crearon ratones que carecían del FXR y que fueron alimentados para desarrollar cálculos biliares. El tratamiento con un fármaco experimental que estimula el citado receptor previno en estos animales la formación de piedras en la vesícula.
Webs Relacionadas
Universität Duisburg-Essen
http://www.uni-duisburg-essen.de/
Nature Medicine
http://www.nature.com/nm/
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Publicado el 5 de diciembre de 2004
Cálculos Biliares
Un fármaco experimental previene la formación de cálculos biliares
El tratamiento con un agente sintético que estimula ciertos receptores que se encuentran en el ácido biliar ha demostrado en ratones prevenir la formación de cálculos biliares, según muestran en "Nature Medicine" investigadores de la Universidad de Texas Southwestern (Estados Unidos).
Los resultados sugieren que el receptor FXR puede ser una diana terapéutica para prevenir o tratar la enfermedad. Los autores crearon ratones que carecían del FXR y que fueron alimentados para desarrollar cálculos biliares. El tratamiento con un fármaco experimental que estimula el citado receptor previno en estos animales la formación de piedras en la vesícula.
Webs Relacionadas
Universität Duisburg-Essen
http://www.uni-duisburg-essen.de/
Nature Medicine
http://www.nature.com/nm/