Estudios con animales muestran que una dosis del fármaco permanece en los pulmones de ratones durante unos pocos días, donde protege frente a un virus similar al de la viruela.
Los autores destacan que el cidofovir puede destruir una amplia variedad de virus, si bien se trata de un fármaco cuyo uso se ha limitado por sus potenciales efectos secundarios renales.
No obstante, la forma inhalada permite aumentar sus niveles en el pulmón y reducirlos en el riñón, lo que conllevaría un menor riesgo de efectos adversos.
Webs Relacionadas
US Army Medical Research Institute of Infectious Diseases
http://www.usamriid.army.mil/
Antimicrobial Agents and Chemotherapy
http://aac.asm.org/
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Publicado el 7 de octubre de 2003
Enfermedad de Creutzfeldt-Jakob
Un antiviral muestra en estudios animales ser potencialmente útil para tratar la viruela
El joven de 19 años Jonathan Simms es la primera persona en recibir inyecciones de polisulfato de pentosán directamente en el cerebro, que parecen haber frenado la progresión de la enfermedad
Estudios con animales muestran que una dosis del fármaco permanece en los pulmones de ratones durante unos pocos días, donde protege frente a un virus similar al de la viruela.
Los autores destacan que el cidofovir puede destruir una amplia variedad de virus, si bien se trata de un fármaco cuyo uso se ha limitado por sus potenciales efectos secundarios renales.
No obstante, la forma inhalada permite aumentar sus niveles en el pulmón y reducirlos en el riñón, lo que conllevaría un menor riesgo de efectos adversos.
Webs Relacionadas
US Army Medical Research Institute of Infectious Diseases
http://www.usamriid.army.mil/
Antimicrobial Agents and Chemotherapy
http://aac.asm.org/