Los resultados de un nuevo artículo publicado en "The New England Journal of Medicine", subestudio del Women's Health Initiative Estrogen-Alone Trial, muestran que las mujeres posmenopáusicas más jóvenes que reciben terapia hormonal sustitutiva (THS) presentan menos placas de calcio en sus arterias en comparación con mujeres de su misma edad que no reciben este tratamiento.
Según la Dra. Elizabeth G. Nabel, directora del Instituto Nacional del Corazón, Pulmón y Sangre (NHLBI) de Estados Unidos, el estudio ofrece tranquilidad a las mujeres posmenopáusicas más jóvenes que preferirían utilizar THS a corto plazo para aliviar los síntomas de la menopausia.
La investigación se realizó sobre una muestra de 1.064 mujeres que tenían entre 50 y 59 años al inicio del estudio, distribuidas aleatoriamente para recibir 0,625 mg diarios de estrógenos equinos conjugados o placebo. Las participantes recibieron la medicación durante una media de 7,5 años. Al cabo de un año, aproximadamente, de finalizar el tratamiento, fueron sometidas a un TAC para medir los niveles de placas de calcio en sus coronarias. Observaron que las tratadas con THS tenían entre 30 y 40% menos probabilidades de presentar niveles de calcio detectables en estas arterias respecto a las que recibieron placebo.
New England Journal of Medicine 2007;356:2591-2602
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