Publicado el 12 de agosto de 2003
Menopausia y desórdenes respiratorios durante el sueño
Terapia de reemplazo hormonal y desórdenes respiratorios durante el sueño
La prevalencia de los desórdenes respiratorios durante el sueño se incrementa con la menopausia.
Autor/a: Dres. Manber R, Kuo TF, Cataldo N, Colrain IM.
Fuente: Sleep. 2003 Mar 15;26(2):163-8.
women: effects of gender. Am J Respir Crit Care Med 2001;163:608-613.
2. Polo-Kantola P, Erkkola R, Helenium H, Irjala K, Polo O. When does estrogen replacement
therapy improve sleep quality? Am J Obst Gynecol 1998;178:1002-1009.
3. Polo-Kantola P, Rauhala E, Saaresranta T, Aittokallio T, Erkkola R, Polo O. Climacteric
vasomotor symptoms do not predict nocturnal breathing abnormalities in postmenopausal
women. Maturitas 2001;39:29-37.
4. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of
estrogen plus progestin in healthy postmenopausal women. JAMA 2002;288:321-333.
5. Carr BR. HRT management: the American experience. Eur J Obstet Gynecol Reprod
Biol 1996;64:S17-20.
6. Manber R, Armitage R. Sex, steroids, and sleep: a review. Sleep 1999;22:540-555.
7. Rupprecht R, Reul J, Trapp T et al. Progesterone receptor-mediated effects of neuroactive
steroids. Neuron 1993;11:523-530.
8. Majewska MD, Harrison NL, Schwartz RD, Barker JL, Paul SM. Steroid hormone
metabolites are barbiturate-like modulators of the GABA receptor. Science
1986;232:1004-1007.
9. Keefe DL, Watson R, Naftolin F. Hormone replacement therapy may alleviate sleep
apnea in menopausal women: a pilot study. Menopause 1999;6:196-200.
10. Dolly FR, Block AJ. Medroxyprogesterone acetate and COPD. Effect on breathing and
oxygenation in sleeping and awake patients. Chest 1983;84:394-398.
11. Sutton FDJ, Zwillich CW, Creagh CE, Pierson DJ, Weil JV. Progesterone for outpatient
treatment of Pickwickian syndrome. Ann Intern Med 1975;83:476-947.
12. Rajagopal KR, Abbrecht PH, Jabbari B. Effects of medroxyprogesterone acetate in
obstructive sleep apnea. Chest 1986;90:815-821.
13. Skatrud JB, Dempsey JA, Iber C, Berssenbrugge A. Correction of CO2 retention during
sleep in patients with chronic obstructive pulmonary diseases. Am Rev Respir Dis
1981;124:260-268.
14. Zwillich CW, Natalino MR, Sutton FD, Weil JV. Effects of progesterone on chemosensitivity
in normal men. J Lab Clin Med 1978;92:262-269.
15. Regensteiner JG, Woodward WD, Hagerman, DD H et al. Combined effects of female
hormones and metabolic rate on ventilatory drives in women. J Appl Physiol
1989;66:808-813.
16. Hannhart B, Pickett CK, Moore LG. Effects of estrogen and progesterone on carotid
body neural output responsiveness to hypoxia. J Appl Physiol 1990;68:1909-1916.
17. Brownell L, West P, Kryger M. Breathing during sleep in normal pregnant women. Am
Rev Respir Dis 1986;133:38-41.
18. Orr WC, Imes NK, Martin RJ. Progesterone therapy in obese patients with sleep apnea.
Arch Intern Med 1979;139:109-111.
19. Cook WR, Benich JJ, Wooten SA. Indices of severity of obstructive sleep apnea syndrome
do not change during medroxyprogesterone acetate therapy. Chest 1989;92:262-
266.
20. Strohl KP, Hensley MJ, Saunders NA, Scharf SM, Brown R, Ingram RHJ. Progesterone
administration and progressive sleep apneas. JAMA 1981;245:1230-1232.
21. Collop NA. Medroxyprogesterone acetate and ethanol-induced exacerbation of obstructive
sleep apnea. Chest 1994;106:792-799.
22. Canto RG, Wiegand L. Hormonal influences on sleep induced upper airway collapsibility
in normal men. Am J Respir Crit Care Med 1993;147:A767.
23. Popovic RM, White DP. Upper airway muscle activity in normal women: influence of
hormonal status. J Appl Physiol 1998;84:1055-1062.
24. Block AJ, Wynne JW, Boysen PG, Lindsey S, Martin C, Canton B. Menopause, medroxyprogesterone
and breathing during sleep. Am J Med 1981;70:506-510.
25. Cistulli PA, Barnes DJ, Grunstein RR, Sullivan CE. Effect of short-term hormone
replacement in the treatment of obstructive sleep apnoea in postmenopausal women.
Thorax 1994;49:699-702.
26. Pickett C, Regensteiner JG, Woodward WD, Hagerman DD, Weil JV, Moore LG. Progestin
and estrogen reduce sleep-disordered breathing in postmenopausal women. J Appl
Physiol 1989;66:1656-1661.
27. The international classification of sleep disorders: diagnostic and coding manual. American
Sleep Disorders Association: Rochester, MN, 1997.
28. Yen SS. Estrogen and the menopause. Am Fam Physician 1977;16:87-89.
29. Diagnostic and Statistical Manual of Mental Disorders (4th ed.). Washington: American
Psychiatric Association, 1994.
30. Sheehan D, Janavs R, Baker K, Harnett-Sheehan E, Knapp E, Sheehan M. MINI International
Neuropsychiatric Interview. Medical Outcome System Inc., 1998.
31. Corson SL. A practical guide to prescribing estrogen replacement therapy. Int J Fertil
1999;40:229-247.
32. Simon JA, Robinson DE, Andrews MC et al. The absorption of oral micronized progesterone:
the effect of food, dose proportionality, and comparison with intramuscular progesterone.
Fertil Steril 1993;60:26-33.
33. Rechtschaffen A, Kales A, eds. A manual of standardized terminology, techniques and
scoring system for sleep stages of human subjects. Los Angeles: UCLA Brain Information
Service/Brain Research institute, 1968.
34. Sleep-related breathing disorders in adults: recommendations for syndrome definition
and measurement techniques in clinical research. A Report from an American Academy
Of Sleep Medicine Task Force. Sleep 1999;22:667-689.
35. Watson D, Clark LA. Development and validation of brief measures of positive and negative
affect: The PANAS Scales. J Pers Soc Psychol 1988;54:1063-1070.
36. Gee K, Bolger M, Brinton R, Coirini H, McEwen B. Steroid modulation of the chloride
ionophore in rat brain: structure-activity requirements, regional dependence, and mechanism
of action. J Pharmacol Exp Ther 1988;246:803-812.
37. Selye H. Acquired adaptation to the anesthetic effect of steroid hormones. J Immunol
1941;41:259-268.
38. Janson C, Noges E, Svedberg-Randt S, Lindberg E. What characterizes patients who are
unable to tolerate continuous positive airway pressure (CPAP) treatment? Respir Med
2000;94:145-9.
39. Kribbs NB, Pack AI, Kline LR et al. Objective measurement of patterns of nasal CPAP
use by patients with obstructive sleep apnea. Am Rev Respir Dis 1993;147:887-895.
40. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of
estrogen plus progestin in healthy postmenopausal women. JAMA 2002;288:321-333.
41. Young T, Peppard P, Palta M et al. Population-based study of sleep-disordered breathing
as a risk factor for hypertension. Arch Intern Med 1997;157:1746-1752.
42. Brodeur P, Mockus M, McCullough R, Moore LG. Progesterone receptors and ventilatory
stimulation by progestin. J Appl Physiol 1986;60:590-595.
43. Friess E, Tagaya H, Trachsel L, Holsboer F, Rupprecht R. Progesterone-induced changes
in sleep in male subjects. Am J Physiol 1997;272:E885-891.
44. Popovic R, White D. Influence of gender on waking genioglossal electromyogram and
upper airway resistance. Am J Respir Crit Care Med 1995;152:725-773.
45. Baer L, Ahern DK. Statistical problems with small sample size. Am J Psychiatry
1993;150:356.
46. Riniolo TC, Schmidt LA. Searching for reliable relationships with statistics packages:An empirical example of the potential problems. J Psychol 2000;134:143-151.