Dietas con suplementos de soja podría ser eficaz para retrasar la progresión de la retinopatía diabética, según informó el Dr. Mike Cooney, del Duke University Eye Center (Estados Unidos), durante la reunión de Macula 2006, celebrada en Nueva York.
Refiriéndose a trabajos experimentales, el Dr. Cooney señaló que la isoflavona genisteína podría ser eficaz para prevenir el inicio temprano de la progresión de la retinopatía diabética, que por ahora suele tratarse en estadios más avanzados.
La genisteína tiene una buena biodisponibilidad y un buen perfil de seguridad. Funciona como un antioxidante y como inhibidor de la reductasa aldosa, enzima que transforma la glucosa en sorbitol, un alcohol glucósido que en grandes cantidades puede culminar en retinopatía y en neuropatía.
En estudios de isquemia, la genisteína ha demostrado que puede inhibir el trayecto de la proteína cinasa tirosina y procurar una protección neurorretiniana. Según el Dr. Cooney, también se observado que reduce la actividad de los receptores del factor de crecimiento endotelial vascular.
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