Inspire Pharmaceuticals ha interrumpido dos ensayos clínicos en fase II de un fármaco que ha desarrollado para el tratamiento del edema macular. En un comunicado, la compañía se ha referido a los dos ensayos piloto de la inyección intravítrea de tetrasodio de denufosol que comenzaron en 2005.
En uno de los ensayos, se seleccionaron 15 pacientes con edema macular persistente asociado a uveítis. En estos pacientes, no se produjo una mejoría demostrable en cuanto a reducción del grosor retiniano o a agudeza visual.
En el segundo ensayo, proyectado para estudiar el efecto del fármaco en pacientes con edema macular persistente, tras operación de cataratas, no llegaron a reclutarse los pacientes.
La compañía no tiene planes para realizar nuevos estudios de denufosol para tratamiento de enfermedad retiniana, pero continuará monitorizando los pacientes tratados para su seguridad, durante un año.
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