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La investigación aparece en la edición electrónica de "Nature Medicine" y describe el mecanismo molecular de resistencia a la terapia antiandrogénica.
Comentan que esta terapia casi siempre funciona bien durante cierto período en los pacientes con cáncer de próstata, pero a menudo fracasa al cabo de un tiempo.
Investigaron el problema en ratones y comprobaron que el único cambio observado, asociado a la resistencia al tratamiento, tiene lugar en la expresión del gen para el receptor del andrógeno.