Tres de un total de diez pacientes a los que se administró Oncophage en un estudio piloto siguen vivos entre 2 y 5 años después del tratamiento, proporción considerable si tenemos en cuenta que más del 95% de los afectados por cáncer de páncreas fallecen antes de los dos años posteriores al diagnóstico.
Según el Dr. Robert Maki, que ha presentado los resultados en la Conferencia Europea de Cáncer (ECCO12) en Copenhague (Dinamarca), "son datos muy preliminares pero al menos son prometedores".
Los diez pacientes fueron cuidadosamente escogidos para el estudio y todos presentaban tumores operables. La supervivencia media fue de 2,5 años. Se les administraron 4 vacunas a lo largo de un mes y el tratamiento se inició 8 semanas después de la intervención quirúrgica. Ninguno de los pacientes recibió quimioterapia ni radioterapia.
La vacuna personalizada se basa en proteínas de choque térmico, que están implicadas en la respuesta del sistema inmunitario, y se derivan de los tumores de cada paciente.
Webs Relacionadas
Memorial Sloan-Kettering Cancer Center
http://www.mskcc.org/
ECCO 12. European Cancer Conference
http://www.fecs.be/
Información sobre Oncophage
http://www.antigenics.com/products/cancer/oncophage/
Antigenics Inc
http://www.antigenics.com/
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