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Los autores, de la Universidad de Cincinnati (Estados Unidos), explican que más de un 50% de los pacientes no responden a los fármacos que han demostrado ser efectivos.
La presente investigación evaluó el tratamiento con aripiprazol –que fue autorizado el pasado año por la FDA estadounidense para tratar la esquizofrenia- comparado a placebo en un grupo de 262 pacientes con trastorno bipolar con un episodio agudo maníaco o mixto. Todos ellos fueron hospitalizados al menos las dos primeras semanas de tratamiento. El fármaco dio lugar a una mayor mejora, medida mediante una escala que valora el grado de manía. El 40% de los participantes tratados con aripiprazol mejoró frente a sólo el 19% del grupo placebo.
Webs Relacionadas
University of Cincinnati
http://www.uc.edu/
American Journal of Psychiatry
http://ajp.psychiatryonline.org/