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En esta ocasión se han utilizado células dendríticas que contienen el virus de la inmunodeficiencia del simio (VIS) inactivado. Tomaron células dendríticas de 20 macacos rhesus infectados por el VIS, las mezclaron en el laboratorio con virus inactivados y posteriormente se inyectaron en los animales tres veces en intervalos de dos semanas.
Los simios experimentaron una fuerte respuesta inmunitaria que dio lugar a un descenso de la carga viral y a un incremento de los linfocitos CD4.