La CBC está indicada tanto para tratar los síntomas de insuficiencia coronaria como para prolongar la expectativa de vida. Los resultados de los estudios aleatorios de CBC versus angioplastia, han demostrado la mayor eficacia del primero para eliminar la angina reduciendo la necesidad de un segundo procedimiento.
La segunda indicación importante de la CBC es prolongar la expectativa de vida. Esto se ha logrado especialmente en aquellos pacientes que requirieron cirugía por lesiones de tronco no protegido de la coronaria izquierda y en la revascularización de múltiples vasos coronarios. El empleo progresivo de conductos arteriales (arterias mamarias, radial y epigástrica), ha prolongado la vida media de permeabilidad de los puentes y contribuido a una mayor expectativa de vida.
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