Participaron en el estudio 1.133 mujeres embarazadas y 992 de sus hijos, a los tres días del nacimiento. A las madres se les administró neviparina y zidovudina durante las 28 semanas de gestación. Los resultados demostraron que los descendientes de estas mujeres tenían mucho menos posibilidades de nacer con el virus del sida que los niños que sólo fueron tratados con zidovudina.
A la luz de estos datos positivos, el Comité de Vigilancia de seguridad de estudio consideró que "lo más apropiado era detener con el brazo del estudio de desarrollo sólo de zidovudina", según explicó la Dra. Sophie Le Coeur, del Institut National D'Etudes Demographiques, de París .
Las conclusiones del estudio también indicaron que la administración de neviparina en combinación con el antirretroviral ZDV para el tratamiento de las infecciones VIH-1 es segura.
Según fuentes de Boehringer Ingelheim Pharmaceuticals, en anteriores ensayos clínicos, Viramune ha demostrado reducir el riesgo de transmisión de la madre al hijo en un 50%. Dicha compañía farmacéutica ha decidido ofrecer su fármaco sin impuestos a los países en vías de desarrollo, durante un período de 5 años.
Webs Relacionadas
Institut National D'Etudes Demographiques
http://www.ined.fr/
Boehringer Ingelheim Pharmaceuticals
http://www.boehringer-ingelheim.com/
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