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Entre 1999 y 2000, los investigadores reclutaron a 155 mujeres con un primer episodio de tromboembolismo venoso, incluyendo 92 casos de embolismo venoso y 63 de trombosis venosa profunda, y los compararon con 381 pacientes control.
En el momento de la inclusión en el estudio, el 21% de las mujeres con tromboembolismo venoso y el 7% de los controles recibían terapia estrogénica oral, mientras que el 19% de las mujeres con TEV y el 24% de los controles recibían terapia estrogénica por vía transdérmica. Tras el ajuste de variables de confusión, los datos mostraron que las mujeres que usaban terapia estrogénica oral tenían tres veces mayor riesgo de desarrollar un TEV que las que empleaban la vía transdérmica (OR: 4,0; IC: 95%, 1,8-6,8) y las que no usaban este tipo de tratamiento (OR: 3,5; IC: 95%, 1,8-6,8).
Webs Relacionadas
Lancet
http://www.thelancet.com/
Inserm
http://www.inserm.fr/