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El fármaco, comercializado como Remicade, inhibe el factor de necrosis tumoral alfa (FNT alfa), que parece desempeñar un papel clave en la inflamación que caracteriza la enfermedad de Crohn. Cuando se autorizó su uso en 1998 se demostró que una única infusión del fármaco comportaba un alivio sintomático a corto plazo, pero la nueva investigación ha querido comprobar su efectividad administrándolo cada 8 semanas a lo largo de un año.
Los resultados muestran que aquellos que han respondido a una dosis única en un plazo de 2 semanas tienen más probabilidades de mantenerse en remisión si continúan el tratamiento.
El estudio incluyó a 335 pacientes que habían respondido a una infusión única, y fueron distribuidos para seguir recibiendo el fármaco o placebo.
Webs Relacionadas
The Lancet
http://www.thelancet.com/
Información sobre Remicade (infliximab)
http://www.remicade.com/