Según los científicos, la combinación de dos variaciones de los polimorfismos del gen colágeno 1 en la configuración de la matriz ósea supone un alto riesgo de contraer la enfermedad. La osteoporosis viene determinada en un 80% por la carga genética del individuo. Pero, al ser una enfermedad poligénica, que depende de más de un gen, quedan por delante todavía nuevas investigaciones que analicen el resto de genes que puedan marcar esta predisposición.
Este avance médico servirá para detectar precozmente la enfermedad y poder realizar tratamientos de forma preventiva. Hay que recordar que la osteoporosis, sólo en España, afecta actualmente a 2 millones de mujeres posmenopáusicas.
El siguiente paso de los especialistas del Hospital del Mar será trabajar con grupos de investigación de Escocia y de Estados Unidos, con el objetivo de realizar un estudio genético a gran escala financiado por la UE.
Webs Relacionadas
Hospital del Mar
http://www.se-fc.org/
Journal of Bone and Mineral Research
http://www.jbmr-online.org/
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