En el último número de "Nature" científicos de la Universidad de Yale anuncian haber identificado una proteína que promueve la regeneración de las fibras nerviosas en ratas con lesión de la médula espinal.
Explican que en el cerebro y la médula espinal existe un inhibidor llamado Nogo que impide la regeneración de las fibras nerviosas tras la lesión. Sin embargo, han descubierto un péptido, bautizado como NEP1-40, que bloquea los efectos del Nogo al unirse a su receptor en el cerebro.
En su experimento, observaron que liberar directamente el péptido en la médula espinal de las ratas, estos animales recuperaron cierta capacidad para volver a caminar.
En comparación con ratas no tratadas, las que recibieron el tratamiento mostraron seguir en mejores condiciones al cabo de un mes.
En opinión de los autores, podría desarrollarse un agente terapéutico de acción similar para su uso en humanos, que promoviera la regeneración nerviosa en lesionados medulares o afectados por traumatismos craneales e ictus.
Webs Relacionadas
Yale University
http://www.yale.edu/
Nature
http://www.nature.com/
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