La proteína se llama disferlina, y se encuentra mutada en dos tipos distintos de distrofia muscular, la conocida como miopatía de Miyoshi y la distrofia muscular de tipo b2 que afecta a las extremidades.
La investigación, publicada en "Nature", sugiere que en estas enfermedades la progresiva degeneración muscular se debe a un defecto en el mecanismo de reparación de los músculos y no a una debilidad inherente de la integridad estructural de los mismos. Por ello, los autores consideran haber descubierto una nueva causa celular de las distrofia muscular que puede conducir a muchos hallazgos sobre la función muscular normal y a terapias con que tratar estos trastornos.
Webs Relacionadas
University of Iowa
http://www.uiowa.edu/
Nature
http://www.nature.com/Nature/
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