Los genes parecen jugar un papel significativo en la predisposición de desarrollar retinopatía de prematuridad (ROP), según un estudio de investigadores de la Yale University School of Medicine (Estados Unidos), recogido por la revista “Pediatrics”.
El equipo del Dr. Vineet Bhandari hizo un estudio retrospectivo sobre la contribución de los factores de riesgo de la ROP en 200 mellizos, nacidos después de una media de 29 semanas de gestación .
Utilizando un análisis de regresión logística, los autores hallaron que la edad gestacional y la duración del suplemento de oxígeno eran significativos factores de riesgo de ROP. Sin embargo, después de controlar factores no genéticos conocidos y desconocidos, descubrieron que el 70,1% de riesgos de la ROP era de responsabilidad genética .
Futuros modelos intervencionales de la ROP deberán limitar los riesgos ambientale e identifica y precisar los factores genéticos, según ha manifestado el Dr. Bhandari.
Pediatrics 2006;118:1858-1863
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