Los investigadores examinaron los posibles efectos de ácido aminosalicílico 5 (5-ASA), metronidazol, ciprofloxacino, prednisona, 6-mercaptopurina, azatioprina y ciclosporina, sobre mujeres embarazadas. Treinta y nueve de ellas sufrían colitis ulcerativa; 73, enfermedad de Crohn; y una colitis indeterminada.
De las 113 pacientes, 16 tuvieron abortos espontáneos (14%); 6, partos prematuros (5%); 2, embarazos ectópicos (1,8%); 1, parto múltiple (0,9%); y 86, partos a término (76%). Tres de los neonatos (2,7%) presentaban defectos mayores, que incluían ano no perforado, defecto cardíaco no detectado y pulmones inmaduros.
Los autores concluyen que en las 113 pacientes con 207 concepciones ninguno de los fármacos utilizados para tratar la EII estuvo asociado a malos resultados del embarazo, si se comparan los índices con los de la población general.
Webs Relacionadas
University of Toronto
http://www.utoronto.ca/
Mount Sinai School of Medicine
http://www.mssm.edu/
American Journal of Gastroenterology
http://www.amjgastro.com/
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